- Summit
- South Shore
- Spring Creek
- Stickney
- Stockholm
- Stone Bridge
- Sevenmile Corner
- Spring Valley Colony
- Spring Lake Colony
- Smiths Park
- Savoy
- Shindler
- Saint Johns Island (historical)
- Stanley Corner
- Spring Creek Colony
- Spain
- Sulphur
- Summerset
- Shannon Colony
- Silver Valley Addition
- Skyline Heights
- Sorum Addition
- Sorum Heights
- Split Rock Heights
- Swanson’s Tracts
- Sioux Falls Junction
- Schaeferville
- Sioux Village
- South Canyon Country Estates
- Stratosphere Bowl