- Shelbina
- Sampsel
- Silverleaf
- Springhill
- Sturges
- Shell Knob
- Shoal Creek Drive
- Shoal Creek Estates
- Sikeston
- Silex
- Slater
- South Greenfield
- South Lineville
- South Van Buren
- South West City
- Spanish Lake
- Spickard
- Stanberry
- Stark City
- Steelville
- Stewartsville
- Strother
- Stotesbury
- Stotts City
- Stoutland
- Stover
- Sturgeon
- Sugar Creek
- Saratoga
- Simcoe